Author: admin
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FlowScore
Summary of article published in The Lancet, full article can be viewed here. The study “Assessing the kinetics of oxygen-unloading from red cells using FlowScore” introduces a new tool, FlowScore, which is a flow-cytometric surrogate for assessing the functional quality of red blood cells (RBCs) in terms of oxygen unloading. Unlike traditional methods that measure oxygen-carrying…
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Innovations in Blood Transfusion Will Save Lives
by Henry Miller Henry I. Miller, a physician and molecular biologist, is the Glenn Swogger Distinguished Fellow at the American Council on Science and Health. An official at the FDA for 15-years, he was the founding director of its Office of Biotechnology. Blood transfusion is one of the cornerstones of modern medicine, used in a…
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Red Blood Cell (RBC) Storage Lesions and Their Clinical Consequences
Red blood cells (RBCs) are essential for multicellular life, delivering oxygen to tissues that cannot obtain it directly from the air. To achieve this, RBCs are specialized with high concentrations of hemoglobin, lack nuclei and organelles, and have a limited lifespan of approximately 120 days in humans. During their circulation, RBCs are adept at carrying oxygen…
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Summary of Red Blood Cell Transfusion and Rejuvesol® Solution
Red Blood Cells (RBCs) and Oxygen Transport Red blood cells (RBCs) are responsible for oxygen (O2) transport throughout the body. Oxygen binds to hemoglobin (Hb) within the RBCs, and the effective delivery of oxygen to tissues depends on two essential molecules: 2,3-diphosphoglycerate (2,3-DPG) and adenosine triphosphate (ATP). 2,3-DPG plays a key role in modulating the release…